DrM designed the STERIBAC® candle filter specifically for the pharmaceutical, biotech and food industries where GMP shall be followed. These industries have to adhere to strict regulatory agency requirements relating to particle shedding and sterility and require reliably clean and sterile solid-liquid separation steps. The STERIBAC® filter design is derived from the well known FUNDABAC® automatic filter which has been applied in thousands of applications in which the capture of solid particles from liquid streams is required and dry cake discharge is regarded as advantageous. The task of scale-up of solid-liquid separation process steps in the pharmaceutical and bio-process industries must combine the sophistication for programming that can be validated with the simplicity of design and construction. STERIBAC® applications include the separation of biomass from fermenter slurries, the separation of precipitated solids in downstream processing lines, activated carbon treatment of liquid product streams, heterogeneous catalyst separation from hydrogenation reactions, the capture of cell debris of both mammalian and bacterial cells, the removal of precipitates in enzymes and plasma, protein fractions, the separation of phases in blood substitutes, as well as crystal separation of injectable antibiotics. For inquiries or further information, please complete and return one of our Application Questionnaires.
Summary & Advantages
- A totally enclosed system for high-containment tasks devoid of mechanically moving parts
- Automation of all filtration steps
- Simple, modular construction of the filter elements
- Mobile and flexible design for short production cycles and frequent batch changes
- Dry, slurry or reslurried discharge of sterile solids into a sterilized container
- Washing liquid waste minimization due to the patented spray washing system
- Patented heel volume filtration allows for virtually 100% recovery of both solid and liquid heel and assures batch integrity
- Cake washing allows for recovery of valuable mother liquor and/or discharge of solids without undesired liquid impurities
- Easy SIP, CIP and disassembly of all components for inspection
- Easy handling of filter cake for washing, drying and discharge
- Filter media that are fully compatible with the product
- Used in the production of particulate free injectables
- All connections of the sanitary tubing to meet O-ring sealed GMP flange requirements
- Selection of process-focussed sterile pump and instruments
Typical Applications